Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.46 |
| ▸ | TUBB | P07437 | 4/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.46 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.46 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.46 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.46 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.46 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802024 | 0.90 | KMT2A (0.46) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7622499 | 0.87 | CYP1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7622494 | 0.87 | CYP1A1 (0.57) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7621487 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7621478 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7621431 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7621435 | 0.83 | KDM4E (0.51) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7620386 | 0.81 | NPC1 (0.50) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL7620399 | 0.81 | NPC1 (0.50) | KDM4EALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL1589647 | 0.78 | PSEN1 (0.65) | KDM4EALDH1A1KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | claimed |