Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 6/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785475 | 0.87 | MAPKAPK2 (0.33) | MAPKAPK2MAPK14 | |
| Trifluoroacetic Acid SCHEMBL7785571 | 0.85 | MAPKAPK2 (0.35) | MAPKAPK2MAPK14HSD17B1HSD17B2 | |
| SCHEMBL7804019 | 0.85 | MAPKAPK2 (0.35) | MAPKAPK2MAPK14 | |
| SCHEMBL7787476 | 0.79 | MAPKAPK2 (0.39) | MAPKAPK2MAPK14 | |
| SCHEMBL7780311 | 0.78 | MEN1 (0.39) | MAPKAPK2MAPK14 | |
| SCHEMBL7787734 | 0.78 | MAPKAPK2 (0.36) | MAPKAPK2MAPK14 | |
| SCHEMBL7787795 | 0.78 | MAPKAPK2 (0.36) | MAPKAPK2MAPK14 | |
| SCHEMBL27530390 | 0.78 | KMT2A (0.36) | MAPKAPK2HSD17B2 | |
| SCHEMBL7780348 | 0.78 | KMT2A (0.41) | MAPKAPK2MAPK14 | |
| SCHEMBL7784909 | 0.78 | KMT2A (0.41) | MAPKAPK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070703-A1 | Cyclobutene derivatives | Sankyo Company Limited (JP) | 2001-01-24 | — | — | EP | disclosed |