⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12878781 | 0.86 | ADH1B (0.41) | — | |
| SCHEMBL6985162 | 0.76 | — | — | |
| SCHEMBL3321896 | 0.75 | — | — | |
| SCHEMBL1315399 | 0.75 | — | — | |
| SCHEMBL21900916 | 0.73 | ADH1B (0.56) | — | |
| SCHEMBL3316659 | 0.73 | ADH1B (0.56) | — | |
| SCHEMBL9155257 | 0.70 | — | — | |
| SCHEMBL14410535 | 0.69 | — | — | |
| SCHEMBL5254698 | 0.69 | ADH1B (0.42) | — | |
| SCHEMBL26696119 | 0.69 | ADH1B (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023164464-A1 | 5'-MODIFIED CARBOCYCLIC RIBONUCLEOTIDE DERIVATIVES AND METHODS OF USE | SANEGENE BIO USA INC. (US) | 2023-08-31 | — | — | WO | disclosed |
| US-20010001101-A1 | Phenanthroline derivatives | ZENECA LIMITED | 2001-05-10 | — | — | US | disclosed |
| EP-1027351-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5916898-A | ANTIFIBROPROLIFERTIVE, ENZYME INHIBITORS OF PYROLYL 4-HYDROXYLASE, ANTIARTHRITIC AGENTS | ZENECA LIMITED (GB) | 1999-06-29 | — | — | US | disclosed |
| WO-1999021860-A1 | PHENANTHROLINE DERIVATIVES | FIBROGEN, INC. (US) | 1999-05-06 | — | — | WO | disclosed |