Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.67 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.67 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.66 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.66 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | DPP4 | P27487 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.66 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.66 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.66 |
| ▸ | GAPDH | P04406 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.66 |
| ▸ | STAT6 | P42226 | 1/20 | 0.66 |
| ▸ | PI4KA | P42356 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.66 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671788 | 1.00 | AHCY (0.67) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL31680251 | 0.94 | AHCY (0.68) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL397800 | 0.94 | AHCY (0.68) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL2040666 | 0.91 | PRMT5 (0.66) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL10997934 | 0.90 | AHCY (0.65) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL21413837 | 0.90 | PRMT5 (0.64) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL16300875 | 0.90 | PRMT5 (0.64) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL22326785 | 0.90 | PRMT5 (0.64) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL22326787 | 0.90 | PRMT5 (0.64) | AHCYPRMT5WDR77ADORA2AADORA2B | |
| SCHEMBL800346 | 0.90 | PRMT5 (0.64) | AHCYPRMT5WDR77ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6210917-B1 | BY TREATING METHYLTHIOADENOSINE PHOSPHORYLASE DEFICIENT CELLS WITH ADENINE SYNTHESIS INHIBITOR TO DEPLETE THE TARGET CELLS OF ADENOSINE 5'-TRIPHOSPHATE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2001-04-03 | — | — | US | disclosed |
| EP-1034299-A4 | METHOD FOR SUPPRESSING MULTIPLE DRUG RESISTANCE IN CANCER CELLS | UNIV CALIFORNIA (US) | 2001-03-07 | — | — | EP | disclosed |
| EP-1034299-A1 | METHOD FOR SUPPRESSING MULTIPLE DRUG RESISTANCE IN CANCER CELLS | The Regents of the University of California (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999020791-A1 | METHOD FOR SUPPRESSING MULTIPLE DRUG RESISTANCE IN CANCER CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-04-29 | — | — | WO | disclosed |