Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.79 |
| ▸ | RAB9A | P51151 | 2/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.76 |
| ▸ | GAA | P10253 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | ABL1 | P00519 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | ALPI | P09923 | 1/20 | 0.76 |
| ▸ | ALPG | P10696 | 1/20 | 0.76 |
| ▸ | APEX1 | P27695 | 1/20 | 0.76 |
| ▸ | CASP3 | P42574 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | CASP7 | P55210 | 1/20 | 0.76 |
| ▸ | CASP6 | P55212 | 1/20 | 0.76 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.76 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.76 |
| ▸ | HSD17B3 | P37058 | 8/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL124008 | 0.93 | NPC1 (0.91) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL7282654 | 0.91 | NPC1 (0.79) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL7163686 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL8614024 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL10341631 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL8622942 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL8519713 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL10341614 | 0.91 | NPC1 (0.86) | NPC1RAB9AL3MBTL1TDP1GAA | |
| SCHEMBL8733595 | 0.89 | NPC1 (1.00) | NPC1RAB9AL3MBTL1TDP1GAA | |
| Ethylene Glycol SCHEMBL29048411 | 0.88 | NPC1 (0.61) | NPC1RAB9AL3MBTL1TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323303-B1 | POLYMERIZING DIARYLOXY COMPOUND WITH A DIHYDRIC PHENOL COMPOUND IN THE PRESENCE OF A RUTHENIUM (II) OR RUTHENIUM (III) COMPOUND OR COMPLEX; OPTIONALLY IN PRESENCE OF A TETRAALKYL AMMONIUM OR TETRAALKYL PHOSPHONIUM SALT | GENERAL ELECTRIC COMPANY | 2001-11-27 | — | — | US | disclosed |