SCHEMBL780365

SCHEMBL780365

O=C(O)C=CC(=O)OC1(C2CCCCC2)CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 1/20 0.39
GAA P10253 1/20 0.39
HCAR2 Q8TDS4 4/20 0.34
ATM Q13315 1/20 0.34
LMNA P02545 3/20 0.32
TP53 P04637 2/20 0.32
CYP3A4 P08684 2/20 0.32
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
MAPT P10636 1/20 0.32
ALOX15 P16050 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NLRP1 Q9C000 1/20 0.32
GPR55 Q9Y2T6 1/20 0.32
POLB P06746 1/20 0.31
TSHR P16473 4/20 0.30
CYP2C9 P11712 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7543722 1.00 HTT (0.39) HTTSMN1; SMN2NPC1GAAHCAR2
SCHEMBL31190321 1.00 HTT (0.39) HTTSMN1; SMN2NPC1GAAHCAR2
SCHEMBL7543729 1.00 HTT (0.39) HTTSMN1; SMN2NPC1GAAHCAR2
SCHEMBL7543720 0.93 CYP3A4 (0.33) LMNACYP3A4MEN1KMT2ANPSR1
SCHEMBL31190331 0.88 HCAR2 (0.34) HTTSMN1; SMN2NPC1GAAHCAR2
SCHEMBL31190302 0.86 HCAR2 (0.35) HCAR2ATM
SCHEMBL31190309 0.84 HCAR2 (0.36) HCAR2
SCHEMBL31190395 0.84 EPHX1 (0.34) HTTSMN1; SMN2HCAR2
SCHEMBL31190304 0.84 HCAR2 (0.39) HTTSMN1; SMN2HCAR2LMNATP53
SCHEMBL930662 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104245756-B Low formaldehyde vinyl esters/vac emulsion copolymer 塞拉尼斯销售德国有限公司 2018-07-13 CN disclosed
CN-104245834-B The block composite and crystalline blocks composite of functionalization 陶氏环球技术有限责任公司 2017-10-13 CN disclosed
EP-1654331-B1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INT BV (NL) 2013-12-11 EP disclosed
US-20120070571-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2012-03-22 US disclosed
US-8048482-B2 Paint comprising a liquid phase and an active powder phase AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2011-11-01 US disclosed
EP-1833870-B1 DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS DU PONT (US) 2011-05-11 EP disclosed
US-7682665-B2 Durable coating compositions containing novel aspartic amine compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-23 US disclosed
US-7674499-B2 Durable coating compositions containing novel aspartic amine compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-03-09 US disclosed
US-7608303-B2 applying overcoating compositions that are useful as exterior clear finishes for automobiles and trucks; reactive putties; reactive cycloaliphatic norbornane derivative containing methylene amine groups react with polyisocyanate crosslinking agent to form polyurea; pot life, fast curing time E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-10-27 US disclosed
EP-1833871-B1 DURABLE COATING COMPOSITIONS CONTAINING ASPARTIC AMINE COMPOUNDS DU PONT (US) 2008-08-20 EP disclosed
US-20060155053-A1 Durable coating compositions containing novel aspartic amine compounds AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-07-13 US disclosed
US-20060141161-A1 Durable coating compositions containing aspartic amine compounds AXALTA COATING SYSTEMS IP CO. LLC (FORMERLY KNOWN AS U.S. COATINGS IP CO. LLC) 2006-06-29 US disclosed
WO-2006066026-A1 DURABLE COATING COMPOSITIONS CONTAINING NOVEL ASPARTIC AMINE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-06-22 WO disclosed
WO-2006066030-A1 DURABLE COATING COMPOSITIONS CONTAINING ASPARTIC AMINE COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2006-06-22 WO disclosed
EP-1654331-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE Akzo Nobel Coatings International B.V. (NL) 2006-05-10 EP disclosed
WO-2005017054-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2005-02-24 WO disclosed
CN-1461417-A Composition for optical material, optical material and plastic lens NOF CORP (JP) 2003-12-10 CN disclosed
US-5925711-A AQUEOUS TWO-COMPONENT COATING COMPOSITION COMPRISING AS BINDER POLYAMINE PRODUCT OF MICHAEL CONDENSATION BETWEEN UNSATURATED OLIGOESTER AND (CYCLO)ALIPHATIC DIAMINE, WATER DISPERSIBLE POLYISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5521250-A ADDITION POLYMERS CONTAINING EPOXIDE AND ANHYDRIDE GROUPS, DICARBOXYLIC ACIDS AND THEIR ANHYDRIDES AS HARDENERS AND OPTIONAL URETIDIONE CROSSLINKERS; AUTOMOBILE CLEAR COATS;NONYELLOWING, SOLVENT AND CHEMICAL RESISTANT BAYER AKTIENGESELLSCHAFT (DE) 1996-05-28 US disclosed
US-5510444-A FLEXIBLE, DISCOLORATION INHIBITION BAYER AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed