Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7803907 | 1.00 | NPC1 (0.48) | NPC1RAB9AL3MBTL1KMT2ACYP11B1 | |
| SCHEMBL7795956 | 0.88 | NPC1 (0.52) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7795952 | 0.88 | NPC1 (0.52) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7795874 | 0.88 | NPC1 (0.55) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7801087 | 0.88 | NPC1 (0.52) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7795871 | 0.88 | NPC1 (0.55) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7801090 | 0.88 | NPC1 (0.52) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL7803857 | 0.83 | KMT2A (0.54) | NPC1RAB9AKMT2AALDH1A1HTT | |
| SCHEMBL7803856 | 0.83 | KMT2A (0.54) | NPC1RAB9AKMT2AALDH1A1HTT | |
| SCHEMBL7803813 | 0.82 | NPC1 (0.46) | NPC1RAB9AL3MBTL1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |