Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7795874 | 1.00 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7795952 | 0.92 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7795956 | 0.92 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL7801090 | 0.91 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7801087 | 0.91 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7803907 | 0.88 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7803901 | 0.88 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7802537 | 0.88 | KLF10 (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7803857 | 0.87 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7803856 | 0.87 | KMT2A (0.54) | NPC1RAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1097117-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000003975-A2 | ARYL VINYL ETHER DERIVATIVES AND THEIR USE AS HERBICIDES | AVENTIS AGRICULTURE LTD. (GB) | 2000-01-27 | — | — | WO | disclosed |