Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 20/20 | 0.90 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.80 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.80 |
| ▸ | HTR2A | P28223 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6776194 | 0.90 | CCR3 (0.82) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7662809 | 0.89 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7658779 | 0.89 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7653971 | 0.89 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7653976 | 0.89 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7659147 | 0.89 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6770145 | 0.87 | CCR3 (0.84) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7662653 | 0.87 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL6773307 | 0.86 | CCR3 (1.00) | CCR3SLC6A2SLC6A4SLC6A3HTR2A | |
| SCHEMBL7658995 | 0.86 | CCR3 (0.86) | CCR3SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140833-A1 | 2-SUBSTITUTED-4-NITROGEN HETEROCYCLES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Du Pont Pharmaceuticals Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035876-A1 | 2-SUBSTITUTED-4-NITROGEN HETEROCYCLES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | DU PONT PHARMACEUTICALS COMPANY (US) | 2000-06-22 | — | — | WO | disclosed |