SCHEMBL7658779

SCHEMBL7658779

CCCN1CC[C@@H](Cc2ccc(F)cc2)C[C@@H]1CCCNC(=O)Nc1cccc(C(C)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 20/20 1.00
SLC6A2 P23975 15/20 1.00
SLC6A4 P31645 15/20 1.00
SLC6A3 Q01959 15/20 1.00
HTR2A P28223 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653971 1.00 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7659147 1.00 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7653976 1.00 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL7662809 0.94 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL6773194 0.94 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3
SCHEMBL18840948 0.94 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3
SCHEMBL7667502 0.93 CCR3 (0.89) CCR3SLC6A2SLC6A4SLC6A3
SCHEMBL7667508 0.93 CCR3 (0.89) CCR3SLC6A2SLC6A4SLC6A3
SCHEMBL6773307 0.91 CCR3 (1.00) CCR3SLC6A2SLC6A4SLC6A3HTR2A
SCHEMBL26079496 0.91 CCR3 (0.91) CCR3SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118653851-A Method for preventing and controlling rock burst of cavern by lancing and releasing pressure 福州大学 2024-09-17 CN claimed
US-6441001-B1 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-08-27 US claimed
US-12598801-B2 Semiconductor device of physical unclonable function and manufacturing method thereof TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2026-04-07 US disclosed
US-20240387524-A1 SEMICONDUCTOR DEVICE AND MANUFACTURING METHOD THEREOF TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) 2024-11-21 US disclosed
CN-118653851-A Method for preventing and controlling rock burst of cavern by lancing and releasing pressure 福州大学 2024-09-17 CN disclosed
CN-118534025-A Iridium isotope fingerprint-based organic mass spectrometry probe for detecting nitric oxide 四川大学 2024-08-23 CN disclosed
CN-116202320-A Pressure rail ring type gangue decarburizing machine 北京中宏联工程技术有限公司 2023-06-02 CN disclosed
CN-218994014-U Pressure rail ring type gangue decarburizing machine 北京中宏联工程技术有限公司 2023-05-09 CN disclosed
CN-218994056-U Non-pressure rail ring type gangue decarburizing machine 北京中宏联工程技术有限公司 2023-05-09 CN disclosed
CN-112605147-B High-corrosion-resistance and low-potential fin aluminum foil for heat exchanger and manufacturing method thereof 江苏鼎胜新能源材料股份有限公司 2023-03-31 CN disclosed
US-11530979-B2 Multifocal photoacoustic microscopy through an ergodic relay CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2022-12-20 US disclosed
US-20170131282-A1 Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 2017-05-11 US disclosed
US-6441001-B1 2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity BRISTOL-MYERS SQUIBB PHARMA COMPANY 2002-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170131282-A1 Inhibition of Chemokine CCL7 or Receptor CCR3 of Same for the Treatment and Diagnosis of Prostate Cancer CCR3, CCR5, CCR1 CCR3 1/4885SLC6A2 2615/4885SLC6A4 2372/4885
US-12598801-B2 Semiconductor device of physical unclonable function and manufacturing method thereof PIEZO1, CTCF, GJB2 CCR3 3991/4885SLC6A2 1332/4885SLC6A4 2414/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.