SCHEMBL780417

SCHEMBL780417

Fc1cccc(-c2ccccc2F)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.50
PTPN1 P18031 1/20 0.50
TAAR1 Q96RJ0 3/20 0.47
ESR2 Q92731 1/20 0.47
MAOB P27338 1/20 0.45
ACMSD Q8TDX5 1/20 0.44
PDK2 Q15119 2/20 0.44
BACE1 P56817 1/20 0.43
TRPA1 O75762 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
ALOX15 P16050 1/20 0.42
ALOX12 P18054 1/20 0.42
NFKB1 P19838 1/20 0.42
MAPK1 P28482 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525640 1.00 PTPRC (0.50) PTPRCPTPN1TAAR1ESR2MAOB
SCHEMBL14479222 0.92 PTPRC (0.53) PTPRCPTPN1TAAR1ESR2ACMSD
SCHEMBL29628986 0.88 PTPRC (0.55) PTPRCPTPN1ACMSDPDK2BACE1
SCHEMBL12856837 0.88 PTPRC (0.55) PTPRCPTPN1ACMSDPDK2BACE1
SCHEMBL12856709 0.86 PTPRC (0.53) PTPRCPTPN1ACMSDPDK2BACE1
SCHEMBL3048969 0.84 TAAR1 (0.45) TAAR1ESR2MAOBPDK2LMNA
SCHEMBL19503242 0.84 HTT (0.49) TAAR1ESR2MAOBPDK2BACE1
SCHEMBL31168142 0.84 HTT (0.49) TAAR1ESR2MAOBPDK2BACE1
SCHEMBL5777460 0.82 TAAR1 (0.47) PTPN1TAAR1ESR2BACE1KDM4E
SCHEMBL14926547 0.82 CNR1 (0.49) TAAR1ESR2ACMSDPDK2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471813-B1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1996-05-22 EP claimed
US-5308542-A Stability, heat and electrical resistance; dielectic anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-05-03 US claimed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-10333172-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2019-06-25 US disclosed
US-10290901-B2 2019-05-14 US disclosed
US-9608291-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-28 US disclosed
US-20170084955-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2017-03-23 US disclosed
EP-1013629-A1 Preparation process of fluorine subsituted aromatic compound Mitsui Chemicals, Inc. (JP) 2000-06-28 EP disclosed
EP-0471813-B1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1996-05-22 EP disclosed
EP-0471813-B1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1996-05-22 EP disclosed
US-5308542-A Stability, heat and electrical resistance; dielectic anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-05-03 US disclosed
US-5308542-A Stability, heat and electrical resistance; dielectic anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-05-03 US disclosed
US-5308542-A Stability, heat and electrical resistance; dielectic anisotropy MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-05-03 US disclosed
EP-0471813-A1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM. MERCK PATENT GMBH (DE) 1992-02-26 EP disclosed
WO-1991013850-A1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-09-19 WO disclosed
WO-1991013850-A1 4,4'-DISUBSTITUTED 2',3-DIFLUORBIPHENYLS AND LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-09-19 WO disclosed