SCHEMBL3048969

SCHEMBL3048969

Fc1cccc(-c2cccc(F)c2F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.45
ESR2 Q92731 1/20 0.45
PGR P06401 2/20 0.41
MAOB P27338 1/20 0.40
CDC7 O00311 1/20 0.40
ROCK2 O75116 1/20 0.40
MAP4K4 O95819 1/20 0.40
PIM1 P11309 1/20 0.40
PRKACA P17612 1/20 0.40
CDK2 P24941 1/20 0.40
GSK3B P49841 1/20 0.40
HIPK2 Q9H2X6 1/20 0.40
CLK4 Q9HAZ1 1/20 0.40
IRAK4 Q9NWZ3 1/20 0.40
CNR2 P34972 1/20 0.40
PDK2 Q15119 1/20 0.39
IDO1 P14902 2/20 0.39
NOTUM Q6P988 1/20 0.39
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13263066 0.90 TAAR1 (0.55) TAAR1ESR2PGRMAP4K4CNR2
SCHEMBL30525640 0.84 PTPRC (0.50) TAAR1ESR2MAOBCDC7ROCK2
SCHEMBL780417 0.84 PTPRC (0.50) TAAR1ESR2MAOBCDC7ROCK2
SCHEMBL25259029 0.81 PTGER1 (0.42) PGRLMNAMAPTNFKB1MAPK1
SCHEMBL29858359 0.81 PTGER1 (0.42) PGRLMNAMAPTNFKB1MAPK1
SCHEMBL200742 0.79 ALDH1A1 (0.42) CNR2LMNANFKB1MAPK1NFKB2
SCHEMBL8124890 0.79 PGR (0.40) PGRMAP4K4PIM1CDK2GSK3B
SCHEMBL25277672 0.79 PGR (0.39) PGRMAP4K4PIM1CDK2GSK3B
SCHEMBL4527011 0.79 RPS6KA3 (0.45) PGRMAOBMAP4K4PIM1PRKACA
SCHEMBL31067144 0.79 TAAR1 (0.42) TAAR1ESR2MAOBCDC7ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3425025-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2021-03-03 EP disclosed
EP-3434750-B1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-11-18 EP disclosed
EP-3663379-A1 LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL LIGHT CONTROL ELEMENT JNC Corporation (JP) 2020-06-10 EP disclosed
US-20200157426-A1 LIQUID CRYSTAL COMPOSITE AND LIQUID CRYSTAL DIMMING DEVICE JNC CORPORATION (JP) 2020-05-21 US disclosed
EP-3533855-A1 LIQUID CRYSTAL COMPOSITION FOR LIGHT CONTROL USE, AND LIQUID CRYSTAL LIGHT-CONTROLLING ELEMENT JNC Corporation (JP) 2019-09-04 EP disclosed
US-20190256773-A1 LIQUID CRYSTAL COMPOSITION FOR DIMMING AND LIQUID CRYSTAL DIMMING DEVICE JNC CORPORATION (JP) 2019-08-22 US disclosed
EP-3425025-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-01-09 EP disclosed
EP-2251397-A2 Liquid crystalline medium and electrooptical display containing it Merck Patent GmbH (DE) 2010-11-17 EP disclosed