Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | DRD4 | P21917 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.45 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.45 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804403 | 0.89 | DRD4 (0.56) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9011157 | 0.85 | DRD4 (0.63) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL9010973 | 0.83 | DRD4 (0.63) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7814366 | 0.82 | MEN1 (0.50) | TSHRLMNAAVPR1AMEN1POLB | |
| SCHEMBL7811430 | 0.81 | TSHR (0.54) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7811589 | 0.80 | DRD4 (0.55) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7804412 | 0.79 | NPC1 (0.48) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7804380 | 0.77 | KCNA5 (0.52) | NPC1LMNAHPGDKCNA5MEN1 | |
| SCHEMBL7817804 | 0.77 | NPC1 (0.54) | NPC1RAB9ADRD4TSHRLMNA | |
| SCHEMBL7811611 | 0.76 | NPC1 (0.56) | NPC1RAB9ADRD4TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |