Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 4/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811667 | 0.92 | KMT2A (0.47) | KCNA5NPC1ALDH1A1LMNAHPGD | |
| SCHEMBL7804403 | 0.88 | DRD4 (0.56) | NPC1ALDH1A1LMNAHPGDHTT | |
| SCHEMBL23268667 | 0.86 | ACHE (0.55) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL7804443 | 0.83 | MEN1 (0.52) | ALDH1A1KDM4ELMNAHTTUSP2 | |
| SCHEMBL10871010 | 0.82 | ACHE (0.60) | ACHEALDH1A1KDM4ESMN1; SMN2HPGD | |
| SCHEMBL7804396 | 0.77 | NPC1 (0.54) | KCNA5NPC1LMNAHPGDMEN1 | |
| SCHEMBL11394317 | 0.77 | KCNA5 (0.58) | KCNA5ACHENPC1ALDH1A1HTT | |
| SCHEMBL7817551 | 0.76 | KCNA5 (0.58) | KCNA5NPC1ALDH1A1KDM4ELMNA | |
| SCHEMBL23268662 | 0.75 | ACHE (0.51) | ACHEALDH1A1KDM4EEPHX1L3MBTL3 | |
| SCHEMBL7804532 | 0.74 | KCNA5 (0.52) | KCNA5NPC1ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| CN-1035178-C | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1997-06-18 | — | — | CN | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| CN-1094039-A | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 1994-10-26 | — | — | CN | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |