Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4703206 | 1.00 | CHRM5 (0.37) | CHRM5ADRA2CSMN1; SMN2HSD11B1CYP2D6 | |
| SCHEMBL7810418 | 1.00 | CHRM5 (0.37) | CHRM5ADRA2CSMN1; SMN2HSD11B1CYP2D6 | |
| SCHEMBL7814375 | 0.98 | CHRM5 (0.40) | CHRM5ADRA2CSMN1; SMN2HSD11B1CYP2D6 | |
| SCHEMBL7804770 | 0.98 | CHRM5 (0.40) | CHRM5ADRA2CSMN1; SMN2HSD11B1CYP2D6 | |
| SCHEMBL2425127 | 0.93 | — | — | |
| SCHEMBL2425189 | 0.93 | — | — | |
| SCHEMBL178341 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL25417087 | 0.91 | GNAI3 (0.37) | SMN1; SMN2CYP2D6CYP1A2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL2427708 | 0.91 | GNAI3 (0.37) | SMN1; SMN2CYP2D6CYP1A2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL3975828 | 0.91 | GNAI3 (0.37) | SMN1; SMN2CYP2D6CYP1A2DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0794184-B1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-05-30 | — | — | EP | disclosed |
| US-5932568-A | GASTROINTESTINAL DISORDERS | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1999-08-03 | — | — | US | disclosed |
| EP-0794184-A1 | 6-METHOXY-1H-BENZOTRIAZOLE-5-CARBOXAMIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITION CONTAINING THE SAME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-09-10 | — | — | EP | disclosed |