Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804540 | 0.89 | AVPR1A (0.55) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7811765 | 0.86 | AVPR1A (0.54) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7804532 | 0.83 | KCNA5 (0.52) | ALDH1A1MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7814140 | 0.81 | NPC1 (0.50) | ALDH1A1MEN1KMT2ALMNAPOLB | |
| SCHEMBL7813987 | 0.80 | ALDH1A1 (0.55) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7813554 | 0.80 | AVPR1A (0.56) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7804443 | 0.78 | MEN1 (0.52) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7804488 | 0.78 | AVPR1A (0.54) | AVPR1AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7813958 | 0.78 | MME (0.47) | MEN1KMT2AUSP2 | |
| SCHEMBL7813501 | 0.76 | ALDH1A1 (0.53) | AVPR1AALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0607536-B1 | Arylamide derivatives | SS PHARMACEUTICAL CO (JP) | 2001-01-24 | — | — | EP | disclosed |
| US-5532371-A | SIDE EFFECT REDUCTION | SS PHARMACEUTICAL CO., LTD. (JP) | 1996-07-02 | — | — | US | disclosed |
| US-5411972-A | Arylamide derivatives for treating hyperlipemia | SS PHARMACEUTICAL CO., LTD. (JP) | 1995-05-02 | — | — | US | disclosed |
| EP-0607536-A1 | Arylamide derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1994-07-27 | — | — | EP | disclosed |