Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565111 | 0.88 | — | — | |
| SCHEMBL6563137 | 0.75 | KLK5 (0.37) | PLGPRSS1PRSS2PRSS3ST14 | |
| SCHEMBL7675036 | 0.74 | F10 (0.42) | PLGPRSS1PRSS2PRSS3NPC1 | |
| SCHEMBL6566092 | 0.71 | KDM1A (0.41) | PLGF2F10PLAUPLAT | |
| SCHEMBL6565512 | 0.70 | GAA (0.40) | PRSS1F2F10PLAUHPGD | |
| SCHEMBL6561984 | 0.70 | MEN1 (0.40) | PLGPRSS1PRSS2PRSS3ST14 | |
| SCHEMBL6561958 | 0.70 | ACACB (0.49) | PLGPRSS1PRSS2PRSS3F2 | |
| SCHEMBL6565349 | 0.70 | F2 (0.38) | PLGPRSS1PRSS2PRSS3ST14 | |
| SCHEMBL6561848 | 0.70 | KDM1A (0.41) | PLGPRSS1PRSS2PRSS3ST14 | |
| SCHEMBL6564290 | 0.69 | ACACB (0.39) | PLGNPC1RAB9AF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |