Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561958 | 0.87 | ACACB (0.49) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL6561944 | 0.84 | F10 (0.43) | ACACBPIK3CAMTOR | |
| SCHEMBL6565512 | 0.83 | GAA (0.40) | F2PRSS1ACACB | |
| SCHEMBL6565424 | 0.80 | ITGB3 (0.42) | F2PRSS1 | |
| SCHEMBL6562282 | 0.80 | PIK3CA (0.44) | F2PLGACACBPIK3CAMTOR | |
| SCHEMBL6564957 | 0.78 | F2 (0.38) | F2PRSS1 | |
| SCHEMBL6565351 | 0.78 | F10 (0.44) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL5885702 | 0.78 | ACACB (0.46) | PRSS1ACACB | |
| SCHEMBL6563137 | 0.77 | KLK5 (0.37) | F2PLGPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL5886024 | 0.77 | ACACB (0.46) | PRSS1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-B1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA (DE) | 2004-03-17 | — | — | EP | disclosed |
| US-6479524-B1 | TO PROLONG THE THROMBIN TIME | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-11-12 | — | — | US | disclosed |