Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | KHK | P50053 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.35 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8033399 | 0.99 | PRMT5 (0.38) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL7804158 | 0.83 | HTR1B (0.50) | ALOX15PRMT5PIK3CDHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL8021880 | 0.82 | HTR1B (0.49) | ALOX15PRMT5PIK3CDHTR1BHTR1A | |
| SCHEMBL19703386 | 0.78 | MEN1 (0.42) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL1869336 | 0.78 | MEN1 (0.49) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL16293090 | 0.78 | SCD (0.49) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL31757809 | 0.78 | MEN1 (0.42) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL15830291 | 0.78 | KDM1A (0.51) | MEN1ALDH1A1MAPTPKMALOX15 | |
| SCHEMBL7808855 | 0.77 | KDM4C (0.36) | KDM1AKHKHTR1BHTR1AHTR1F | |
| SCHEMBL7805945 | 0.77 | DRD4 (0.49) | ALDH1A1KMT2AHTR1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |