Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 4/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR1F | P30939 | 1/20 | 0.50 |
| ▸ | SCD | O00767 | 6/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 4/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8021880 | 0.99 | HTR1B (0.49) | HTR1BHTR1AHTR1FSCDALOX15 | |
| SCHEMBL7804939 | 0.90 | HTR1B (0.43) | HTR1BHTR1AHTR1FSCDALOX15 | |
| Hydrochloric Acid SCHEMBL8031585 | 0.89 | HTR1B (0.42) | HTR1BHTR1AHTR1FSCDALOX15 | |
| SCHEMBL7804909 | 0.83 | MEN1 (0.38) | HTR1BHTR1AHTR1FSCDALOX15 | |
| Hydrochloric Acid SCHEMBL8033399 | 0.82 | PRMT5 (0.38) | HTR1BHTR1AHTR1FSCDALOX15 | |
| SCHEMBL7805945 | 0.80 | DRD4 (0.49) | HTR1BHTR1DDRD2 | |
| SCHEMBL7804097 | 0.80 | KMT2A (0.51) | HTR1BHTR1AHTR1FGAASMN1; SMN2 | |
| SCHEMBL15830330 | 0.80 | HTR1A (0.55) | HTR1BHTR1AHTR1FSCDALOX15 | |
| Hydrochloric Acid SCHEMBL8037880 | 0.79 | DRD4 (0.48) | HTR1BSMN1; SMN2HTR1DDRD2 | |
| SCHEMBL3349663 | 0.79 | HTR1B (0.54) | HTR1BHTR1AHTR1FSCDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0902027-B1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR (FR) | 2001-07-25 | — | — | EP | disclosed |
| EP-0902027-A1 | Indole and indazole derivatives, process for their preparation and the pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-03-17 | — | — | EP | disclosed |