Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812128 | 0.88 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL7812420 | 0.84 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL7198831 | 0.83 | EDNRA (0.49) | EDNRAEDNRB | |
| SCHEMBL8655641 | 0.78 | EDNRA (0.71) | EDNRAEDNRB | |
| SCHEMBL7815181 | 0.78 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL8656735 | 0.77 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL7815226 | 0.76 | EDNRA (0.50) | EDNRAEDNRB | |
| SCHEMBL8657467 | 0.75 | EDNRA (0.79) | EDNRAEDNRB | |
| SCHEMBL9492466 | 0.74 | EDNRA (0.70) | EDNRAEDNRB | |
| SCHEMBL8804693 | 0.73 | EDNRB (0.77) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743307-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| US-5739333-A | 4-SULFONAMIDO-6-ARYLOXY OR -AMINOALKYLENEOXY,-AMINO, OR -THIOPYRIMIDINES; ENDOLTHELIN ANTAGONISTS; HYPOTENSIVE AND ULCER AGENTS; ASTHMA; RAYNAUD DISEASE; CARDIOVASCULAR DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1998-04-14 | — | — | US | disclosed |
| EP-0743307-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |