Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 8/20 | 0.57 |
| ▸ | EDNRB | P24530 | 5/20 | 0.49 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812128 | 0.85 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL7815181 | 0.85 | EDNRA (0.44) | EDNRAEDNRB | |
| SCHEMBL7805397 | 0.84 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL7814428 | 0.84 | EDNRB (0.70) | EDNRAEDNRB | |
| SCHEMBL8656735 | 0.80 | EDNRA (0.70) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL7805440 | 0.77 | EDNRA (0.57) | EDNRAEDNRB | |
| SCHEMBL9492466 | 0.76 | EDNRA (0.70) | EDNRAEDNRBABCC3ABCC4NR1I2 | |
| SCHEMBL8659228 | 0.75 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8657656 | 0.75 | EDNRA (0.72) | EDNRAEDNRB | |
| SCHEMBL8655641 | 0.75 | EDNRA (0.71) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743307-B1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO (JP) | 2001-09-12 | — | — | EP | disclosed |
| EP-0743307-A1 | Sulfonamide derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1996-11-20 | — | — | EP | disclosed |