Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.58 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | TYMP | P19971 | 9/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PYGM | P11217 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8542375 | 1.00 | HSP90AA1 (0.59) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL9229289 | 0.99 | HSP90AA1 (0.60) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL9229284 | 0.99 | HSP90AA1 (0.60) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL8534790 | 0.92 | TYMP (0.62) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL8534788 | 0.92 | TYMP (0.62) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL2580552 | 0.89 | HSP90AA1 (0.56) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL2801918 | 0.89 | HSP90AA1 (0.56) | HSP90AA1P2RY6P2RY14NT5ETYMP | |
| SCHEMBL8535399 | 0.87 | TYMP (0.57) | TYMP | |
| SCHEMBL5953147 | 0.87 | TYMP (0.57) | TYMP | |
| SCHEMBL8535403 | 0.87 | TYMP (0.57) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851866-B1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-5945406-A | ANTICANCER AGENTS; TREATMENT FOR METASTATIC LIVER CANCER, FUNGAL INFECTIONS, PSORIASIS; USED IN MANUFACTURE OF DRUGSTO PREVENT CELL DIVISION | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 1999-08-31 | — | — | US | disclosed |