Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 15/20 | 0.54 |
| ▸ | RARA | P10276 | 14/20 | 0.54 |
| ▸ | RARG | P13631 | 14/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.54 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805647 | 1.00 | RARB (0.54) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7800435 | 0.90 | RARA (0.68) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7800439 | 0.90 | RARA (0.68) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7807998 | 0.89 | RARB (0.58) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7808007 | 0.89 | RARB (0.58) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7805653 | 0.86 | RARB (0.46) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8661442 | 0.79 | RARB (0.40) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7811823 | 0.79 | RARB (0.55) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL7811830 | 0.79 | RARB (0.55) | RARBRARARARGRXRANR2E1 | |
| SCHEMBL8663816 | 0.79 | RARB (0.43) | RARBRARARARGRXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010003780-A1 | Retinoid antagonists and uses thereof | TRAMPOSCH KENNETH M (US) | 2001-06-14 | — | — | US | disclosed |
| WO-1998046228-A1 | RETINOID ANTAGONISTS AND USES THEREOF | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003780-A1 | Retinoid antagonists and uses thereof | RARA, RARB, RARG | RARB 2/4885RARA 1/4885RARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.