Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL5194331 | 0.89 | KDM4E (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL1022681 | 0.88 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E | |
| SCHEMBL1022680 | 0.88 | SLC6A4 (0.56) | SLC6A2SLC6A4SLC6A3KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL1022164 | 0.86 | SLC6A4 (0.55) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL6574968 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1HTR6 | |
| SCHEMBL7215873 | 0.83 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL7809824 | 0.83 | SLC6A3 (0.60) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL1335541 | 0.81 | SLC6A4 (0.58) | SLC6A2SLC6A4SLC6A3HTR6 | |
| SCHEMBL1021888 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3ALDH1A1KMT2A | |
| SCHEMBL7806031 | 0.81 | SLC6A4 (0.80) | SLC6A2SLC6A4SLC6A3KMT2AHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | claimed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | claimed |
| EP-1068204-A1 | 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND USE OF 8-AZABICYCLO 3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 2001-01-17 | — | — | EP | disclosed |
| WO-1999038866-A1 | 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED FORM AND USE OF 8-AZABICYCLO[3.2.1]OCT-2-ENE DERIVATIVES IN LABELLED AND UNLABELLED FORM | NEUROSEARCH A/S (DK) | 1999-08-05 | — | — | WO | disclosed |