Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20180887 | 0.89 | SMN1; SMN2 (0.56) | MAPTSMN1; SMN2P2RX7ALDH1A1KDM4E | |
| SCHEMBL7294542 | 0.89 | MAPT (0.66) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL20091850 | 0.86 | CHEK1 (0.60) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL11117825 | 0.85 | NPC1 (0.59) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL16915136 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL30602445 | 0.85 | MAPT (0.52) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL23997016 | 0.84 | MAPT (0.51) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL12051770 | 0.83 | PKM (0.60) | SMN1; SMN2ALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL24196349 | 0.83 | MAPT (0.56) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL22040205 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2ALDH1A1KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |