SCHEMBL7807016

SCHEMBL7807016

COC(=O)CCCc1ccc(NC(=O)c2ccc3ccc(OCc4ccc5ccccc5n4)cc3c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 8/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7801457 0.98 CYSLTR1 (0.84) CYSLTR1
SCHEMBL7801698 0.91 CYSLTR1 (1.00) CYSLTR1
SCHEMBL7806848 0.90 CYSLTR1 (1.00) CYSLTR1
SCHEMBL7801727 0.83 CYSLTR1 (0.75) CYSLTR1
SCHEMBL9054244 0.83 CYSLTR1 (0.60) CYSLTR1
SCHEMBL9053620 0.82 CYSLTR1 (0.59) CYSLTR1
SCHEMBL8648449 0.78 FFAR1 (0.76) CYSLTR1
SCHEMBL7810130 0.77 CYSLTR1 (0.79) CYSLTR1
SCHEMBL7801678 0.77 CYSLTR1 (0.70) CYSLTR1
SCHEMBL8736480 0.77 CYSLTR1 (0.96) CYSLTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0775133-B1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION MENARINI LAB (ES) 2001-05-30 EP disclosed
EP-0775133-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1997-05-28 EP disclosed
WO-1996004267-A1 NAPHTHALENE AMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1996-02-15 WO disclosed