SCHEMBL9053620

SCHEMBL9053620

COC(=O)CCCc1ccc(NC(=O)Cc2cccc(OCc3ccc4ccccc4n3)c2)cc1

nearest known ligand 0.84

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYSLTR1 Q9Y271 4/20 0.59
CYSLTR2 Q9NS75 2/20 0.58
ALOX5 P09917 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9054244 0.91 CYSLTR1 (0.60) CYSLTR1CYSLTR2ALOX5
SCHEMBL9057805 0.90 CYSLTR1 (0.59) CYSLTR1CYSLTR2ALOX5
SCHEMBL7801457 0.83 CYSLTR1 (0.84) CYSLTR1CYSLTR2
SCHEMBL9053379 0.82 ALOX5 (0.72) CYSLTR1CYSLTR2ALOX5
SCHEMBL7807016 0.82 CYSLTR1 (0.84) CYSLTR1
SCHEMBL9054564 0.81 CYSLTR1 (0.60) CYSLTR1CYSLTR2ALOX5
SCHEMBL7801727 0.81 CYSLTR1 (0.75) CYSLTR1
SCHEMBL8180018 0.80 CYSLTR2 (0.67) CYSLTR1CYSLTR2
SCHEMBL9053636 0.79 CYSLTR1 (0.54) CYSLTR1CYSLTR2
SCHEMBL10636003 0.78 CYSLTR1 (0.75) CYSLTR1CYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996004246-A1 PHENYLACETAMIDES HAVING LEUKOTRIENE-ANTAGONISTIC ACTION LABORATORIOS MENARINI S.A. (ES) 1996-02-15 WO disclosed