Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 19/20 | 0.50 |
| ▸ | CTSL | P07711 | 15/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7805843 | 1.00 | CTSS (0.50) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL1138974 | 0.88 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL1138853 | 0.88 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL1139649 | 0.88 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL1139016 | 0.88 | CTSS (0.64) | CTSSCTSLCTSK | |
| SCHEMBL7807911 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSK | |
| SCHEMBL3793817 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3796086 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3798567 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3802602 | 0.85 | CTSS (0.49) | CTSSCTSLCTSBCTSKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010142650-A1 | NOVEL CYCLOPENTANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-12-16 | — | — | WO | disclosed |