SCHEMBL7807286

SCHEMBL7807286

Cc1ccc(-c2cc(N)ccc2N(CCO)CCO)s1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 1/20 0.35
MPI P34949 1/20 0.35
KMT2A Q03164 1/20 0.35
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
GFER P55789 1/20 0.33
HSD17B10 Q99714 1/20 0.33
PDE10A Q9Y233 1/20 0.31
GRIN2B Q13224 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7807688 0.84
SCHEMBL7809799 0.84 GRIN2B (0.31) MEN1KMT2ANPC1GRIN2B
SCHEMBL7807421 0.82 CYP2A6 (0.37)
SCHEMBL7807504 0.82 ALDH1A1 (0.37) ALDH1A1MEN1KMT2AMAPT
SCHEMBL7812222 0.80 DPP4 (0.33) MEN1KMT2A
SCHEMBL7692527 0.80 ALDH1A1 (0.32) ALDH1A1PDE10A
SCHEMBL7456909 0.77 ALDH1A1 (0.35) ALDH1A1PDE10A
SCHEMBL6570740 0.77 ALDH1A1 (0.38) ALDH1A1MEN1KMT2ANPC1MAPT
SCHEMBL7800933 0.76 NPC1 (0.38) ALDH1A1MEN1KMT2ANPC1MAPT
SCHEMBL7460684 0.76 CYP2A6 (0.37) ALDH1A1MEN1KMT2APDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed