Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | STK4 | Q13043 | 1/20 | 0.30 |
| ▸ | STK3 | Q13188 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812329 | 0.84 | MAPT (0.36) | KMT2AMAPTMEN1LMNASMN1; SMN2 | |
| SCHEMBL7808744 | 0.80 | MAPT (0.36) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL7808894 | 0.76 | MEN1 (0.32) | KMT2AMAPTMEN1GAASTK4 | |
| SCHEMBL7809775 | 0.76 | MEN1 (0.32) | KMT2AMAPTMEN1GAASTK4 | |
| SCHEMBL7465818 | 0.76 | KMT2A (0.36) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL7800694 | 0.76 | MEN1 (0.32) | KMT2AMAPTMEN1STK4STK3 | |
| SCHEMBL7805928 | 0.74 | KMT2A (0.39) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL7800654 | 0.74 | MAPT (0.39) | KMT2AMAPTMEN1LMNATP53 | |
| SCHEMBL7808552 | 0.74 | CYP3A4 (0.45) | KMT2AMEN1CDK2 | |
| SCHEMBL7809608 | 0.72 | MAPT (0.38) | KMT2AMAPTMEN1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |