Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7812154 | 0.86 | MAPT (0.36) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7808513 | 0.81 | MAPT (0.35) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7456698 | 0.78 | KMT2A (0.35) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7800650 | 0.78 | CRHR1 (0.32) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7807699 | 0.78 | RORC (0.32) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7808527 | 0.78 | CRHR1 (0.32) | MAPTKMT2AMEN1GAAPKM | |
| SCHEMBL7808458 | 0.75 | CYP3A4 (0.42) | MAPTKMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL7808559 | 0.73 | MEN1 (0.31) | KMT2AMEN1 | |
| SCHEMBL7800920 | 0.73 | MAP4K4 (0.34) | MAPT | |
| SCHEMBL7807385 | 0.72 | KMT2A (0.39) | MAPTKMT2AMEN1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |