Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736680 | 0.67 | — | — | |
| SCHEMBL7807059 | 0.66 | LMNA (0.33) | KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL20475242 | 0.65 | MAPK1 (0.55) | KDM4EMAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL30206047 | 0.64 | KDM5A (0.34) | SMN1; SMN2 | |
| Bromide SCHEMBL20475245 | 0.64 | MAPK1 (0.53) | KDM4EMAPK1MEN1ALDH1A1KMT2A | |
| SCHEMBL16962884 | 0.63 | DHODH (0.33) | ALDH1A1 | |
| SCHEMBL11317106 | 0.61 | — | — | |
| SCHEMBL16832256 | 0.60 | ADORA2A (0.39) | KDM4EMAPK1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6211365 | 0.60 | PDE4D (0.32) | KDM4EMAPK1MEN1KMT2A | |
| SCHEMBL1229075 | 0.58 | TDP1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124827-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | Dow AgroSciences LLC (US) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000024739-A1 | 3-(SUBSTITUTED PHENYL)-5-(SUBSTITUTED HETEROCYCLYL)-1,2,4-TRIAZOLE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |