⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17971245 | 0.77 | — | — | |
| SCHEMBL7807669 | 0.75 | — | — | |
| SCHEMBL7807681 | 0.75 | — | — | |
| SCHEMBL5936772 | 0.68 | — | — | |
| SCHEMBL21081839 | 0.65 | — | — | |
| SCHEMBL5164389 | 0.65 | — | — | |
| SCHEMBL28550319 | 0.65 | — | — | |
| SCHEMBL5694135 | 0.64 | ALDH1A1 (0.31) | — | |
| SCHEMBL412699 | 0.64 | — | — | |
| SCHEMBL1773637 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027353-A4 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-1027353-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | Merck & Co., Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5994343-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1999-11-30 | — | — | US | disclosed |
| WO-1999018107-A1 | CARBAPENEM ANTIBACTERIAL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK & CO., INC. (US) | 1999-04-15 | — | — | WO | disclosed |