SCHEMBL7807697

SCHEMBL7807697

Cc1cc(N)c(-c2cccs2)cc1N(CCO)CCO

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
GAA P10253 2/20 0.36
KEAP1 Q14145 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 1/20 0.36
ATM Q13315 1/20 0.36
SLC6A9 P48067 1/20 0.35
KCNH2 Q12809 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HDAC1 Q13547 6/20 0.34
HDAC3 O15379 5/20 0.34
HDAC2 Q92769 5/20 0.34
AR P10275 2/20 0.34
NR3C1 P04150 1/20 0.34
PGR P06401 1/20 0.34
KDM4E B2RXH2 3/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7807264 0.84 AR (0.39) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7808454 0.84 NPC1 (0.36) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7809761 0.77 NPC1 (0.40) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7800933 0.77 NPC1 (0.38) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7807514 0.77 NPC1 (0.41) ALDH1A1MAPTGAANPC1RAB9A
SCHEMBL7808501 0.76 NPC1 (0.39) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7459640 0.76 CYP2A6 (0.39) ALDH1A1MAPTSLC6A9KCNH2HSD17B10
SCHEMBL7809743 0.76 NR3C1 (0.36) ALDH1A1MAPTGAAKEAP1NPC1
Hydrochloric Acid SCHEMBL7807540 0.76 NPC1 (0.38) ALDH1A1MAPTGAAKEAP1NPC1
SCHEMBL7807583 0.75 KCNH2 (0.46) ALDH1A1MAPTGAAKEAP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed