SCHEMBL7807940

SCHEMBL7807940

C=Cc1ccc2c(c1)C(C)(C)c1[nH]c3cc(N)ccc3c1C2=O

nearest known ligand 0.72

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALK Q9UM73 20/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL897044 0.84 ALK (1.00) ALK
SCHEMBL1755913 0.82 ALK (0.52) ALK
SCHEMBL1755955 0.80 ALK (0.52) ALK
SCHEMBL7805101 0.80 ALK (0.72) ALK
SCHEMBL7802172 0.80 ALK (0.51) ALK
SCHEMBL1755850 0.78 ALK (0.58) ALK
SCHEMBL7813872 0.78 ALK (0.74) ALK
SCHEMBL7799907 0.77 ALK (0.59) ALK
SCHEMBL24675629 0.77 ALK (0.60) ALK
SCHEMBL1755799 0.77 ALK (0.73) ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010143664-A1 TETRACYCLIC COMPOUND 中外製薬株式会社 (JP) 2010-12-16 WO disclosed