Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.40 |
| ▸ | GOPC | Q9HD26 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6283862 | 0.79 | CFTR (0.41) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23354817 | 0.76 | CFTR (0.38) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6491522 | 0.76 | CYP19A1 (0.41) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8873323 | 0.75 | SMN1; SMN2 (0.41) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8643958 | 0.73 | SMN1; SMN2 (0.40) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21143806 | 0.72 | CYP19A1 (0.37) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23354868 | 0.72 | CNR1 (0.41) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2559305 | 0.70 | CFTR (0.52) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24933822 | 0.70 | SMN1; SMN2 (0.42) | CFTRGOPCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23354901 | 0.69 | ALDH1A1 (0.42) | SMN1; SMN2KDM4EGAALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6881736-B1 | Vitronectin receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 2005-04-19 | — | — | US | disclosed |