Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 13/20 | 0.52 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810557 | 0.85 | TBXA2R (0.56) | TBXA2RTBXAS1CYSLTR1LTB4R | |
| SCHEMBL7808405 | 0.85 | TBXA2R (0.71) | TBXA2RTBXAS1CYSLTR1 | |
| SCHEMBL7808478 | 0.81 | TBXA2R (0.59) | TBXA2RTBXAS1 | |
| SCHEMBL7806801 | 0.81 | CYSLTR1 (0.42) | TBXA2RCYSLTR1LTB4R | |
| SCHEMBL7802376 | 0.81 | TBXA2R (0.49) | TBXA2RTBXAS1CYSLTR1LTB4R | |
| SCHEMBL8825027 | 0.80 | TBXA2R (0.47) | TBXA2RCYSLTR1LTB4R | |
| SCHEMBL8825049 | 0.80 | LTB4R (0.40) | TBXA2RCYSLTR1LTB4R | |
| SCHEMBL7813406 | 0.80 | LTB4R (0.43) | TBXA2RTBXAS1CYSLTR1LTB4R | |
| SCHEMBL8825056 | 0.78 | LTB4R (0.42) | TBXA2RTBXAS1LTB4R | |
| SCHEMBL7806920 | 0.77 | CYSLTR1 (0.54) | TBXA2RTBXAS1ADAMTS4CYSLTR1LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0685478-B1 | QUINOLINE DERIVATIVES | UBE INDUSTRIES (JP) | 2001-10-24 | — | — | EP | disclosed |
| US-5591752-A | LEUKOTRIENE ANTAGONIST, ANTIALLERGEN, ANTIINFLAMMATORY AGENT, DIBENZ(B,E)OXEPINE | UBE INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0685478-A1 | QUINOLINE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1995-12-06 | — | — | EP | disclosed |