Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 11/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.68 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.50 |
| ▸ | CCKAR | P32238 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526270 | 0.81 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKAR | |
| SCHEMBL9526276 | 0.81 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKAR | |
| SCHEMBL9525366 | 0.81 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKAR | |
| SCHEMBL9525360 | 0.81 | CCKBR (1.00) | CCKBRKCNH2SCN9ACCKAR | |
| SCHEMBL8880870 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A | |
| SCHEMBL8880864 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A | |
| SCHEMBL9008767 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A | |
| SCHEMBL9008763 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A | |
| SCHEMBL8879465 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A | |
| SCHEMBL9303610 | 0.81 | CCKBR (0.69) | CCKBRKCNH2SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652871-B1 | BENZODIAZEPINE DERIVATIVES | MERCK SHARP & DOHME (GB) | 2001-10-17 | — | — | EP | disclosed |
| US-5618812-A | GASTRIN ANTAGONISTS; GASTROINTESTINAL DISORDERS | MERCK SHARP & DOHME, LTD. (GB) | 1997-04-08 | — | — | US | disclosed |