SCHEMBL7808370

SCHEMBL7808370

CC(C)(C)c1ccc(OCC2COC(c3ccccc3Cl)=N2)cc1

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
TAAR1 Q96RJ0 1/20 0.40
GRM2 Q14416 2/20 0.39
TP53 P04637 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
TSHR P16473 2/20 0.39
CYP1A2 P05177 1/20 0.39
ALDH1A1 P00352 1/20 0.39
PPARG P37231 1/20 0.39
HIF1A Q16665 1/20 0.39
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
RAB9A P51151 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803678 0.84 TAAR1 (0.40) MEN1KMT2ATAAR1GRM2TP53
SCHEMBL7808814 0.79 TP53 (0.40) MEN1KMT2ATAAR1GRM2TP53
SCHEMBL8890986 0.79 TAAR1 (0.46) TAAR1
SCHEMBL8894624 0.74 TAAR1 (0.46) TAAR1
SCHEMBL7812577 0.73 TAAR1 (0.43) TAAR1TP53MAPTHPGDALDH1A1
SCHEMBL23956826 0.72 MAPT (0.50) TAAR1MAPTALDH1A1POLBRAB9A
SCHEMBL8892138 0.69 TAAR1 (0.45) TAAR1
SCHEMBL23230265 0.67 TAAR1 (0.45) MEN1KMT2ATAAR1MAPTPOLB
SCHEMBL7803670 0.66 TAAR1 (0.37) TAAR1GRM2
SCHEMBL2530840 0.66 ALDH1A1 (0.81) MEN1KMT2AGRM2TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP claimed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US claimed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP claimed
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed