SCHEMBL7808377

SCHEMBL7808377

Fc1cccc(F)c1C1=NC(COc2ccc(-c3ccc(Br)cc3)cc2)CO1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
RAB9A P51151 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 1/20 0.46
TAAR1 Q96RJ0 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812313 0.90 TAAR1 (0.40) NPC1POLBRAB9ASMN1; SMN2MAPT
SCHEMBL7810550 0.88 MAPT (0.43) NPC1RAB9ASMN1; SMN2MAPTTAAR1
SCHEMBL7809993 0.88 TAAR1 (0.46) NPC1RAB9ATAAR1
SCHEMBL7810324 0.88 TAAR1 (0.39) NPC1RAB9ATAAR1
SCHEMBL7812996 0.86 TAAR1 (0.47) TAAR1
SCHEMBL7815858 0.86 TAAR1 (0.37) NPC1POLBRAB9ASMN1; SMN2MAPT
SCHEMBL7803670 0.86 TAAR1 (0.37) TAAR1
SCHEMBL7810332 0.86 TAAR1 (0.37) TAAR1
SCHEMBL8309476 0.85 TAAR1 (0.48) TAAR1
SCHEMBL7812242 0.85 TAAR1 (0.46) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed