SCHEMBL7809993

SCHEMBL7809993

Fc1cccc(F)c1C1=NC(COc2ccc(-c3ccc(Cl)cc3)cc2)CO1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.46
NPC1 O15118 1/20 0.39
CASP3 P42574 1/20 0.39
RAB9A P51151 1/20 0.39
SENP8 Q96LD8 1/20 0.39
SENP7 Q9BQF6 1/20 0.39
SENP6 Q9GZR1 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
FFAR1 O14842 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812996 0.93 TAAR1 (0.47) TAAR1
SCHEMBL7803617 0.93 TAAR1 (0.46) TAAR1
SCHEMBL7816156 0.91 TAAR1 (0.51) TAAR1FFAR1
SCHEMBL7812313 0.90 TAAR1 (0.40) TAAR1NPC1RAB9A
SCHEMBL7809030 0.90 TAAR1 (0.46) TAAR1
SCHEMBL7803706 0.89 TAAR1 (0.43) TAAR1
SCHEMBL7808377 0.88 NPC1 (0.46) TAAR1NPC1RAB9A
SCHEMBL7810324 0.88 TAAR1 (0.39) TAAR1NPC1RAB9A
SCHEMBL7810550 0.88 MAPT (0.43) TAAR1NPC1RAB9A
SCHEMBL7812247 0.87 TAAR1 (0.44) TAAR1NPC1CASP3RAB9ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
US-5411979-A Insecticides, miticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-05-02 US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 EP disclosed