Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | TMPRSS6 | Q8IU80 | 4/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.30 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | HPN | P05981 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562003 | 0.92 | PTPN11 (0.33) | CA1CA2PTPN11MALT1AAK1 | |
| SCHEMBL6565916 | 0.85 | ITGB3 (0.35) | F2ITGB3ITGA2BPLAUHPN | |
| SCHEMBL6562499 | 0.85 | ITGB3 (0.34) | F2TMPRSS6ITGB3ITGA2BPLAU | |
| SCHEMBL6563611 | 0.84 | ITGB3 (0.38) | F2ITGB3ITGA2BPLAU | |
| SCHEMBL6561908 | 0.84 | PTPN11 (0.33) | PTPN11AAK1 | |
| SCHEMBL6563607 | 0.84 | ITGB3 (0.40) | F2ITGB3ITGA2BPLAU | |
| SCHEMBL6561947 | 0.83 | F10 (0.36) | F2ITGB3ITGA2BPLAU | |
| SCHEMBL6561873 | 0.83 | ITGB3 (0.38) | F2ITGB3ITGA2B | |
| SCHEMBL4250003 | 0.82 | ITGB3 (0.37) | F2TMPRSS6ITGB3ITGA2BPLAU | |
| SCHEMBL6563542 | 0.82 | ITGB3 (0.37) | F2ITGB3ITGA2BPLAUHPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140802-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM KG (DE) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035859-A1 | SUBSTITUTED ARYL AND HETEROARYL DERIVATIVES, THEIR PRODUCTION AND THEIR USE AS MEDICINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-06-22 | — | — | WO | disclosed |