Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099970 | 0.83 | KDM4E (0.32) | KDM4EALDH1A1GAAPCSK9NPC1 | |
| SCHEMBL7809795 | 0.74 | — | — | |
| SCHEMBL7463019 | 0.74 | — | — | |
| SCHEMBL8103648 | 0.71 | — | — | |
| SCHEMBL7455880 | 0.69 | — | — | |
| SCHEMBL7800827 | 0.69 | KCNH2 (0.37) | KDM4EALDH1A1NPC1 | |
| SCHEMBL30884734 | 0.64 | — | — | |
| SCHEMBL197196 | 0.64 | PCSK9 (0.60) | KDM4EALDH1A1GAAPCSK9NPC1 | |
| SCHEMBL2971120 | 0.60 | PCSK9 (0.36) | KDM4EALDH1A1GAAPCSK9NPC1 | |
| SCHEMBL3188837 | 0.59 | PCSK9 (0.50) | KDM4EALDH1A1GAAPCSK9NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943614-B1 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | WELLA AG (DE) | 2001-12-12 | — | — | EP | disclosed |
| US-6042620-A | FOR DYEING KERATIN FIBERS SUCH AS HAIR | WELLA AG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0943614-A2 | Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives | Wella Aktiengesellschaft (DE) | 1999-09-22 | — | — | EP | disclosed |