SCHEMBL7808563

SCHEMBL7808563

Cc1ccoc1-c1cc(N)ccc1N(CCO)CCO

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
PDE10A Q9Y233 1/20 0.33
MAPK14 Q16539 1/20 0.32
TSHR P16473 1/20 0.30
CASP1 P29466 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7809828 0.85
SCHEMBL7808506 0.84 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7462605 0.83 ALDH1A1 (0.33) ALDH1A1PDE10A
SCHEMBL7800787 0.83
SCHEMBL7807709 0.82 CHRM2 (0.33) ALDH1A1
SCHEMBL7807482 0.81
SCHEMBL7464469 0.77
SCHEMBL8100528 0.77 ALDH1A1 (0.32) ALDH1A1
SCHEMBL7458662 0.77
SCHEMBL7459407 0.77 ALDH1A1 (0.35) ALDH1A1PDE10ATSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0943614-B1 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives WELLA AG (DE) 2001-12-12 EP disclosed
US-6042620-A FOR DYEING KERATIN FIBERS SUCH AS HAIR WELLA AG (DE) 2000-03-28 US disclosed
EP-0943614-A2 Dyeing agents comprising diaminobenzene derivatives and the diaminobenzene derivatives Wella Aktiengesellschaft (DE) 1999-09-22 EP disclosed