Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 19/20 | 0.64 |
| ▸ | PTGER2 | P43116 | 19/20 | 0.64 |
| ▸ | PTGER4 | P35408 | 17/20 | 0.64 |
| ▸ | PTGER1 | P34995 | 10/20 | 0.64 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.39 |
| ▸ | PTGFR | P43088 | 3/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Ethanol SCHEMBL7809006 | 1.00 | PTGER3 (0.64) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7966447 | 0.97 | PTGER3 (0.67) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7966444 | 0.97 | PTGER3 (0.67) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7809005 | 0.88 | PTGER3 (0.56) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7961831 | 0.88 | PTGER3 (0.56) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7805026 | 0.76 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7805023 | 0.76 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7804201 | 0.75 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7804198 | 0.75 | PTGER2 (1.00) | PTGER3PTGER2PTGER4PTGER1TBXA2R | |
| SCHEMBL7804187 | 0.72 | PTGER2 (0.83) | PTGER3PTGER2PTGER4PTGER1TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119542-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | Merck Frosst Canada & Co. (CA) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020371-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | MERCK FROSST CANADA & CO. (CA) | 2000-04-13 | — | — | WO | disclosed |