Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 17/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 17/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 16/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 11/20 | 0.56 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.34 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7966444 | 0.91 | PTGER3 (0.67) | PTGER3PTGER2PTGER4PTGER1HCAR2 | |
| SCHEMBL7966447 | 0.91 | PTGER3 (0.67) | PTGER3PTGER2PTGER4PTGER1HCAR2 | |
| Phenyl Ethanol SCHEMBL7809007 | 0.88 | PTGER3 (0.64) | PTGER3PTGER2PTGER4PTGER1HCAR2 | |
| SCHEMBL7961831 | 0.88 | PTGER3 (0.56) | PTGER3PTGER2PTGER4PTGER1L3MBTL1 | |
| Phenyl Ethanol SCHEMBL7809006 | 0.88 | PTGER3 (0.64) | PTGER3PTGER2PTGER4PTGER1HCAR2 | |
| SCHEMBL9641895 | 0.78 | HCAR2 (0.63) | HCAR2L3MBTL1LTB4RLTB4R2 | |
| SCHEMBL9641909 | 0.78 | HCAR2 (0.63) | HCAR2L3MBTL1LTB4RLTB4R2 | |
| SCHEMBL8011005 | 0.72 | NFE2L2 (0.60) | HCAR2L3MBTL1 | |
| SCHEMBL7957261 | 0.71 | PTGER4 (0.76) | PTGER3PTGER2PTGER4PTGER1 | |
| SCHEMBL7957258 | 0.71 | PTGER4 (0.76) | PTGER3PTGER2PTGER4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119542-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | Merck Frosst Canada & Co. (CA) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000020371-A1 | PROSTAGLANDIN RECEPTOR LIGANDS | MERCK FROSST CANADA & CO. (CA) | 2000-04-13 | — | — | WO | disclosed |