Sugi Predict

Sugi Predict / Compounds / SCHEMBL7809030

SCHEMBL7809030

SCHEMBL7809030

Fc1cccc(F)c1C1=NC(COc2ccc(OCc3ccc(Cl)cc3)cc2)CO1

nearest known ligand 0.56

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TAAR1 Q96RJ0 1/20 0.46
▸ MAOB P27338 6/20 0.43
▸ APP P05067 1/20 0.40
▸ NR4A2 P43354 1/20 0.40
▸ MAOA P21397 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8894014 0.90 TAAR1 (0.45) TAAR1
SCHEMBL7809993 0.90 TAAR1 (0.46) TAAR1
SCHEMBL7803617 0.90 TAAR1 (0.46) TAAR1
SCHEMBL7808755 0.90 TAAR1 (0.47) TAAR1MAOB
SCHEMBL7812632 0.89 NPC1 (0.40) TAAR1MAOBMAOA
SCHEMBL7809985 0.89 MAOB (0.42) TAAR1MAOBAPP
SCHEMBL7812920 0.87 TAAR1 (0.44) TAAR1
SCHEMBL7810243 0.87 MRGPRX4 (0.38) TAAR1
SCHEMBL7812081 0.85 TAAR1 (0.46) TAAR1NR4A2
SCHEMBL24274919 0.84 MAOB (0.43) TAAR1MAOBAPPNR4A2MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0553623-B1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL CO (JP) 2001-04-04 — — EP disclosed
US-5556867-A INSECTICIDES AND MITICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-09-17 — — US disclosed
EP-0553623-A1 An oxazoline derivative its production and its use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-04 — — EP disclosed