Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 3/20 | 0.49 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.49 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.49 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.49 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.41 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191168 | 0.84 | SLC22A6 (0.56) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8192729 | 0.82 | SLC22A6 (0.55) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8181436 | 0.82 | SLC22A6 (0.55) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8191992 | 0.82 | SLC22A6 (0.55) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8181377 | 0.82 | SLC22A6 (0.54) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| Hydrochloric Acid SCHEMBL8145152 | 0.81 | PGR (0.43) | SLC22A6SLC22A8PDE4APDE4BPDE4C | |
| SCHEMBL8191185 | 0.81 | SLC22A6 (0.53) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL7811473 | 0.80 | SLC22A6 (0.52) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8189778 | 0.80 | GRIA1 (0.41) | GRIA1GRIA2GRIA3GRIA4SLC22A6 | |
| SCHEMBL8191257 | 0.79 | SLC22A6 (0.71) | GRIA1GRIA2GRIA3GRIA4SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0784054-B1 | 1,2,3,4-TETRAHYDROQUINOXALINEDIONE DERIVATIVES AND USE AS GLUTAMATE RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMA CO LTD (JP) | 2001-11-28 | — | — | EP | disclosed |
| CN-1067387-C | 1,2,3,4-tetrahydroquinoxalindione derivative | YAMANOUCHI PHARMA CO LTD (JP) | 2001-06-20 | — | — | CN | disclosed |
| US-6096743-A | 1,2,3,4-tetrahydroquinoxalinedione derivative | YAMANOUCHI PHARMACEUTICALS CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |
| CN-1168670-A | 1,2,3,4-tetrahydroquinoxalindione derivative | YAMANOUCHI PHARMA CO LTD (JP) | 1997-12-24 | — | — | CN | disclosed |
| EP-0784054-A1 | 1,2,3,4-TETRAHYDROQUINOXALINEDIONE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1997-07-16 | — | — | EP | disclosed |