Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 15/20 | 0.57 |
| ▸ | SMO | Q99835 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2972175 | 0.92 | MAPK14 (0.60) | MAPK14SMOSETD2 | |
| SCHEMBL6487809 | 0.91 | MAPK14 (0.69) | MAPK14SMORAB9A | |
| SCHEMBL7804539 | 0.89 | MAPK14 (0.56) | MAPK14 | |
| SCHEMBL7852826 | 0.89 | MAPK14 (0.55) | MAPK14SMOSETD2 | |
| SCHEMBL27558565 | 0.87 | MAPK1 (0.57) | MAPK14SMOMEN1KMT2ANPC1 | |
| SCHEMBL7804583 | 0.85 | MAPK14 (0.62) | MAPK14SMOHDAC1MEN1KMT2A | |
| SCHEMBL7780464 | 0.84 | MAPK14 (0.65) | MAPK14SMOHDAC1SETD2RAB9A | |
| SCHEMBL6477438 | 0.83 | MAPK14 (0.67) | MAPK14SMO | |
| SCHEMBL6977502 | 0.83 | MAPK14 (0.56) | MAPK14SMONPC1TP53PKM | |
| SCHEMBL7809428 | 0.82 | ALDH1A1 (0.50) | MAPK14MEN1KMT2APKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077931-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | AstraZeneca AB (SE) | 2001-02-28 | — | — | EP | claimed |
| WO-1999059959-A1 | BENZAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY CYTOKINES | ASTRAZENECA AB (SE) | 1999-11-25 | — | — | WO | claimed |